Tsingke is at the forefront of this innovation, offering high-quality single-stranded DNA synthesis services that significantly enhance gene knock-in efficiency. In the cutting-edge field of gene editing, ssDNA synthesis has emerged as a pivotal technology, particularly for applications involving CRISPR/Cas9. With a focus on delivering comprehensive results and minimizing cytotoxic effects, Tsingke is dedicated to advancing research capabilities for scientists and clinicians.
Comprehensive Service Offerings
Tsingke’s ssDNA synthesis service provides clients with a robust set of deliverables. Each order includes lyophilized product powder, sequencing maps, target sequences, and an electronic Certificate of Analysis (COA) report. This comprehensive documentation ensures that researchers have all the information they need to utilize their synthesized ssDNA effectively, enhancing the overall research experience.
Enhanced Gene Knock-In Efficiency
One of the standout features of Tsingke’s ssDNA synthesis service is its remarkable efficiency in CRISPR/Cas9 gene knock-in applications. Research indicates that ssDNA templates offer a nine-fold higher knock-in efficiency compared to traditional double-stranded DNA (dsDNA) when used as homologous recombination templates. This increased efficiency can lead to more successful genetic modifications, making Tsingke’s solutions invaluable for researchers aiming to achieve precise genetic alterations.
Low Cytotoxicity
Another significant advantage of Tsingke’s ssDNA synthesis is its low cytotoxicity profile. By minimizing adverse effects on cell viability, Tsingke ensures that researchers can conduct experiments with greater confidence. Higher homologous recombination and knock-in efficiency, coupled with reduced cytotoxic effects, provide researchers with a powerful tool for advancing their genetic studies and therapeutic developments.
Conclusion
With a focus on comprehensive service offerings, enhanced efficiency, and low cytotoxicity, Tsingke empowers researchers to achieve their scientific goals with confidence. Tsingke, the company for your ssDNA synthesis needs and experience the transformative impact it can have on your research and development projects.
